Antibiotics that are effective against a wide range of gram-positive and gram-negative
bacteria are known as broad spectrum antibiotics. Chloramphenicol is a broad spectrum antibiotic.

It can be used for the treatment of typhoid, dysentery, acute fever, pneumonia, meningitis, and certain forms of urinary infections. Two other broad spectrum antibiotics are
vancomycin and ofloxacin. Ampicillin and amoxicillin −synthetically modified from penicillin− are also broad spectrum antibiotics.